1. Inkscape
Inkscape is a professional vector graphics editor (SVG format) featuring
transparency, gradients, node editing, pattern fills, PNG export, and
more. for Windows, Mac OS X and Linux. It's free and open source. It is an open-source vector graphics editor similar to Adobe Illustrator, Corel Draw, Freehand, or Xara X. What sets Inkscape apart is its use of Scalable Vector Graphics (SVG), an open XML-based W3C standard, as the native format.
2. GTK+ and GIMP installers for Windows
GIMP is an acronym for GNU Image Manipulation Program. It is a freely distributed program for such tasks as photo retouching, image composition and image authoring.
3. Dia Diagram Editor
Popular general purpose drawing software for Windows, Mac OS X and Linux. Dia supports more than 30 different diagram types like flowcharts, network diagrams, database models. More than a thousand readymade objects help to draw professional diagrams. Dia can read and write a number of different raster and vector image formats. Software developers and database specialists can use Dia as a CASE tool to generate code skeletons from their drawings. Dia can be scripted and extended using Python.
4. Paintbrush
Paintbrush is a simple paint program for Mac OS X, reminiscent of Microsoft Paint and Apple’s own now-defunct MacPaint. It provides users with a means to make simple images quickly, something that has been noticeably absent from the Mac for years.
5. Tux Paint
Tux Paint is a free, award-winning drawing program for children ages 3 to 12. It combines an easy-to-use interface, fun sound effects, and an encouraging cartoon mascot who guides children as they use the program. Kids are presented with a blank canvas and a variety of drawing tools to help them be creative. Along with paintbrush, shapes and text, Tux Paint includes a "stamp" feature to add pre-drawn or photographic imagery to pictures, and a set of "magic tools" that provide filter effects (like blur, tint and waves) and interesting drawing tools (like train tracks, bubbles and grass). Tux Paint includes a collection of "starter" images, both coloring-book style and photo-realistic, and a large collections of stamps are available as a separate download. Additional content can be added by parents and teachers, or downloaded from 3rd parties. Tux Paint is available for Linux, BSD, Windows, Mac OS X and Haiku operating systems.